Cortexa research tool·genomics·ensembl_compara

EnsemblCompara Get Orthologues

Find orthologous genes (genes in different species that evolved from a common ancestor) using Ensembl Compara. Essential for comparative genomics - finding the mouse, zebrafish, or fly equivalent of a human gene. Returns orthologue gene IDs, species, homology type (one-to-one, one-to-many), and taxonomy level of divergence. Example: TP53 in human has a one-to-one orthologue (Trp53) in mouse.

Livelast probed 2026-05-01 01:00Z· 2370msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 2370ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "gene": {
      "description": "Gene symbol or Ensembl gene ID. Examples: 'BRCA1', 'TP53', 'ENSG00000141510', 'ENSG00000012048'.",
      "type": "string"
    },
    "species": {
      "description": "Source species (default: 'human'). Examples: 'human', 'mouse', 'zebrafish', 'drosophila_melanogaster'.",
      "type": "string"
    },
    "target_species": {
      "description": "Target species to limit orthologue search. Examples: 'mouse', 'zebrafish', 'rat', 'drosophila_melanogaster'. Default: all species.",
      "type": "string"
    },
    "target_taxon": {
      "description": "NCBI taxon ID to limit orthologue search. Examples: 10090 (mouse), 7955 (zebrafish), 7227 (fruit fly). Alternative to target_species.",
      "type": "integer"
    }
  },
  "required": [
    "gene"
  ],
  "type": "object"
}

Examples (1)

Default EnsemblCompara Get Orthologues call

public-safeinput

{
  "gene": "BRCA1",
  "target_taxon": 1
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_EnsemblCompara_get_orthologues
Tool name: EnsemblCompara_get_orthologues
Added: 2026-05-01 00:58Z
Tags: tooluniverse

EnsemblCompara Get Orthologues

Livelast probed 2026-05-01 01:00Z· 2370msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "gene": { "description": "Gene symbol or Ensembl gene ID. Examples: 'BRCA1', 'TP53', 'ENSG00000141510', 'ENSG00000012048'.", "type": "string" }, "species": { "description": "Source species (default: 'human'). Examples: 'human', 'mouse', 'zebrafish', 'drosophila_melanogaster'.", "type": "string" }, "target_species": { "description": "Target species to limit orthologue search. Examples: 'mouse', 'zebrafish', 'rat', 'drosophila_melanogaster'. Default: all species.", "type": "string" }, "target_taxon": { "description": "NCBI taxon ID to limit orthologue search. Examples: 10090 (mouse), 7955 (zebrafish), 7227 (fruit fly). Alternative to target_species.", "type": "integer" } }, "required": [ "gene" ], "type": "object" }