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Cortexa
Research hub
Translational neurologist·Drugs · Trials · Genomics

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PubMedClinicalTrials.govFDA labelsOpenAlex
Cortexa is researching
Built forResearchers·Engineers·Clinicians·Analysts·Founders·Grad students
Also available inSlack·API·more on the way
Features

One agent across
every discipline

Cortexa reads your artifacts, queries verified evidence, runs the analysis, and keeps every claim in the final answer cited — across biomedical, clinical, genomics, chemistry, structures, AI, physics, engineering, materials, energy, and policy work.

Autonomous Research Agent

Ask a complex question in any discipline — Cortexa plans the approach, picks the right sources for the domain, queries them in parallel, cross-references results, and synthesizes a cited brief. Dozens of tool calls, zero babysitting.

Literature & Evidence Synthesis

Queries arXiv, Semantic Scholar, PubMed, bioRxiv, and domain-specific archives simultaneously. Returns ranked evidence with inline citations, not a list of links.

Life-Sciences Depth

Fetches structures from AlphaFold and PDB, runs variant lookups in ClinVar, Open Targets analyses, and visualizes 3D conformations — all inside the conversation.

Trials, Patents & Policy

Parses recruiting trials, patent landscapes, and regulatory guidance. Returns matched records with IDs, assignees, deadlines, and the primary source — ready to act on.

Clinical Evidence Intake

Drop in radiology reports, lab panels, pathology notes, genomics reports, or clinical summaries. Cortexa detects the artifact, extracts what the report actually states, preserves uncertainty and negations, then connects the findings to cited literature, guidelines, trials, labels, and coding systems. Built for research context — not diagnosis or treatment orders.

Runs the Analysis, Not Just the Search

When a question needs a number — power calculations, hazard ratios, regressions, custom plots from a public dataset — Cortexa writes Python and runs it in the Cortexa compute sandbox. NumPy, pandas, SciPy, scikit-learn, statsmodels, and matplotlib are pre-installed; figures and tables come back inline as artifacts. Real computation, fully cited inputs, no pasting code into another tab.

Safety, Grounded in the Right Domain

Cortexa applies the right safety frame per question — research-framed clinical caveats, drug-label constraints, ML reproducibility notes, legal jurisdiction warnings, or nothing at all for general academic work.

Inline structures, charts, formulas

When a question deserves a visual, Cortexa renders it inline — molecular structures from PDB / AlphaFold, lightweight charts, LaTeX formulas, and elevated citation cards next to the prose.

API for Agentic Research

OpenAI-compatible endpoint lets your team drop Cortexa into EHRs, lab notebooks, ML training pipelines, patent-review systems, and internal tooling. Metered billing, zero lock-in.

2.2K+
Verified tools
450M+
Scholarly works
All
Disciplines
Integrations

Cortexa, wherever
you already work.

One research agent, reachable from every surface your team lives on. Same plan, same citations, same usage — no matter which one you invoke it from.

The research canvas

The full Cortexa experience — autonomous research, inline structures and charts, and cited briefs you can print or share.

  • Stream tool calls in real time
  • Drop in PDFs, papers, notes
  • Generate a formal research brief
Open the canvas

Cortexa in Slack

@mention Cortexa in any channel, DM it privately, or run /cortexa from the composer. Same agent, same plan, same citations.

  • @cortexa in channels & threads
  • /cortexa from any composer
  • Per-workspace install · SSO-ready
Add to Slack
Beta

Private connections

Bring your own Postgres, S3, GCS, Bitquery, Google Drive, or Box context into Cortexa through encrypted user-scoped connections.

  • Tailored setup forms
  • Encrypted credentials
  • OAuth-ready document apps
Connect your data
New

MCP server

Call Cortexa as a tool from Claude Desktop, Cursor, Codex, Claude Code, Windsurf, Zed — any MCP-capable client. Stdio via npx or hosted streamable-HTTP.

  • npx -y @yoreai/cortexa-mcp
  • Hosted at /mcp for remote clients
  • One cortexa_research tool, cited answers
Configure your client
Beta

Developer API

OpenAI-compatible endpoint for wiring Cortexa into EHRs, lab notebooks, pipelines, or your own chat UI. Metered, no lock-in.

  • Drop-in /v1/chat/completions
  • Usage-based pricing
  • Scoped API keys per environment
View developer docs
On the roadmap

Shipping surfaces is our superpower

Slack went from idea to production in under a week — the Chat SDK under the hood means we can light up another surface fast. Here's what's queued up next.

Request an integration
Microsoft TeamsComing
DiscordComing
LinearComing
Zapier / n8nComing
Chrome extensionComing
VS Code extensionComing
NotionComing
Data Sources

What Cortexa reads from every session

Fifteen research surfaces, one agent. From biomedical to finance, Cortexa picks the right sources for the question, queries them in parallel, and cites every finding in the final brief.

Literature & Preprints

OpenAlex

450M+ works

Crossref

180M+ DOIs

Semantic Scholar

200M+ papers

arXiv

3M+ preprints

Biomedical & Drugs

PubMed

40M+ citations

FDA Drug Labels

Structured FDA labels

ClinicalTrials.gov

525K+ studies

bioRxiv / medRxiv

320K+ preprints

Genomics, Proteins & Targets

UniProt

250M+ sequences

ClinVar

4M+ variants

NCBI Gene

45K+ human genes

Open Targets

75K+ targets

Clinical Evidence

ICD-10/ICD-11

70K+ codes

LOINC

100K+ lab codes

HPO

16K+ phenotypes

Orphanet

6K+ rare diseases

US Providers (NPPES)

8M+ NPIs — BigQuery

Real-World & Public Health

DailyMed

Structured drug labels

MedlinePlus

NIH consumer health

CDC datasets

Surveillance & registries

NHANES

Population health survey

Cancer Genomics & Oncology

TCGA / GDC

11K+ tumor profiles

OncoKB

Actionable variants

COSMIC

Somatic mutations

DepMap

Cancer cell-line dependencies

Structural Biology

RCSB PDB

240K+ experimental

AlphaFold DB

240M+ predicted

ESMFold

On-demand folds

InterPro / Pfam

Domains & families

Chemistry

PubChem

118M+ compounds

ChEMBL

2M+ bioactivities

Chemical identifiers

CAS · InChI · SMILES

Climate, Earth & Environment

NOAA

Weather & climate

USGS

Hydrology & seismic

EPA Envirofacts

Emissions & toxics

NASA EONET

Wildfires · storms · volcanoes

Physics & Astronomy

arXiv (astro-ph, hep-th, …)

3M+ preprints

NASA ADS

Astrophysics literature

Zenodo

4M+ artifacts

Code, Models & Datasets

GitHub

500M+ repos

Hugging Face

2M+ models & datasets

Zenodo (software)

4M+ artifacts

Policy, Patents & Public Records

Patents (PatentsView)

8M+ patents — BigQuery

Patent Litigation

USPTO OCE court cases

SEC EDGAR

Company filings

Federal Register

US rules & notices

World Bank

Global indicators

Law & Regulations

CourtListener

9M+ opinions, RECAP dockets

eCFR

All 50 CFR titles

EUR-Lex

EU treaties, regulations, CJEU

SEC EDGAR

10-K, 10-Q, 8-K, S-1

Congress.gov

Bills, members, votes

Finance & Markets

FRED

800K+ economic series

SEC Financials

XBRL fundamentals

CoinGecko

10K+ crypto markets

Crypto On-Chain

BTC + ETH ledgers — BigQuery

ECB Data Portal

Euro-area FX & rates

BLS

CPI · jobs · wages

Veterinary & Animal Health

openFDA Animal & Vet

CVM adverse events

PubMed (veterinary)

Animal-health literature

FDA animal pharmacology

Tox via Tool Mesh

See every connector and tool in the public catalog→

Pricing

Start free. Upgrade when the research gets serious.

Start free, then step up to Plus, Pro, or Enterprise. Plan management, checkout, and team controls all live inside your Cortexa billing settings after sign-in.

Free

Try the agent with real cited research.

$0/mo

50 credits / month

Start free
  • No credit card required
  • All 2.2K+ verified tools
  • Shareable sessions

Plus

For individual researchers who want real headroom without the Pro commitment.

$25/mo

750 credits / month

Choose Plus
  • Everything in Free
  • 15× the Free credit budget
  • Overage cap you control
Popular

Pro

For regular research work with more credits and overage headroom.

$99/mo

3,000 credits / month

Choose Pro
  • Higher monthly credit budget
  • Overage cap you control
  • Heavier files, tools, and connected-data budgets

Enterprise

For teams that need one shared credit pool, controls, and private data access.

$999/mo

35,000 shared credits / month

Team settings
  • No per-seat pricing to start
  • Shared private connections
  • Member usage visibility
Pay for compute, not seats

One credit maps to actual AI work. Teams share a credit pool instead of paying per seat.

No surprise bills

Free pauses after the included budget. Paid plans can auto-continue at $0.012/credit up to a cap you set.

Same core product on every plan

Every plan — Free, Plus, Pro, and Enterprise — reaches the same 2.2K+ verified tools, files, connections, API, and MCP surface. Credits control usage.

Need details before choosing?

Compare plans after sign-in, including checkout, credits, and team controls.

Compare plans

Ready to accelerate
your research?

Open the agent, ask anything worth knowing, and get a cited brief you can revise and share.

Launch the agent
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Set up in under a minute
Cortexa.

The agent for research teams. 2.2K+ verified tools across every research discipline, every claim cited.

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