Cortexa research tool·genomics·ensembl_ld

EnsemblLD Get Ld Pairwise

Get pairwise linkage disequilibrium (LD) statistics between two specific variants from the Ensembl REST API. Returns r-squared and D' across ALL 1000 Genomes populations, allowing comparison of LD patterns across ancestries. Useful for assessing whether two GWAS signals are correlated or independent. Example: rs6792369 vs rs1042779 shows r2=1.0 in East Asian populations but r2=0.84 in African populations.

Livelast probed 2026-04-30 23:07Z· 98msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 98ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "variant1": {
      "description": "rs ID of the first variant. Examples: 'rs6792369', 'rs429358'.",
      "type": "string"
    },
    "variant2": {
      "description": "rs ID of the second variant. Examples: 'rs1042779', 'rs7412'.",
      "type": "string"
    }
  },
  "required": [
    "variant1",
    "variant2"
  ],
  "type": "object"
}

Examples (1)

Default EnsemblLD Get Ld Pairwise call

public-safeinput

{
  "variant1": "",
  "variant2": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_EnsemblLD_get_ld_pairwise
Tool name: EnsemblLD_get_ld_pairwise
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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