Cortexa research tool·genomics·ensembl_ld

EnsemblLD Get Ld Variants

Get linkage disequilibrium (LD) data for a variant from the Ensembl REST API. Returns all variants in LD with the query variant in a specified 1000 Genomes population, with r-squared and D' statistics. LD measures the non-random association of alleles at different loci, critical for GWAS interpretation and fine-mapping. Example: rs1042779 in KHV population returns 708 LD partners with r2 and D' values.

Livelast probed 2026-04-30 23:07Z· 104msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 104ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "d_prime_threshold": {
      "description": "Minimum D' threshold. Default: none. Set e.g., 0.8 for high D' only.",
      "type": [
        "number",
        "null"
      ]
    },
    "population": {
      "description": "1000 Genomes population. Format: '1000GENOMES:phase_3:<POP>'. Common populations: 'KHV' (Kinh Vietnamese), 'CEU' (CEPH Utah), 'YRI' (Yoruba), 'CHB' (Han Chinese Beijing), 'GBR' (British), 'JPT' (Japanese Tokyo), 'ASW' (African SW US). Example: '1000GENOMES:phase_3:CEU'.",
      "type": "string"
    },
    "r2_threshold": {
      "description": "Minimum r-squared threshold to report. Default: 0.05. Set higher (e.g., 0.8) for strong LD only.",
      "type": [
        "number",
        "null"
      ]
    },
    "variant_id": {
      "description": "rs ID of the variant. Examples: 'rs1042779', 'rs429358', 'rs7903146', 'rs6792369'.",
      "type": "string"
    }
  },
  "required": [
    "variant_id",
    "population"
  ],
  "type": "object"
}

Examples (1)

Default EnsemblLD Get Ld Variants call

public-safeinput

{
  "population": "",
  "variant_id": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_EnsemblLD_get_ld_variants
Tool name: EnsemblLD_get_ld_variants
Added: 2026-04-30 22:47Z
Tags: tooluniverse

EnsemblLD Get Ld Variants

Livelast probed 2026-04-30 23:07Z· 104msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "d_prime_threshold": { "description": "Minimum D' threshold. Default: none. Set e.g., 0.8 for high D' only.", "type": [ "number", "null" ] }, "population": { "description": "1000 Genomes population. Format: '1000GENOMES:phase_3:<POP>'. Common populations: 'KHV' (Kinh Vietnamese), 'CEU' (CEPH Utah), 'YRI' (Yoruba), 'CHB' (Han Chinese Beijing), 'GBR' (British), 'JPT' (Japanese Tokyo), 'ASW' (African SW US). Example: '1000GENOMES:phase_3:CEU'.", "type": "string" }, "r2_threshold": { "description": "Minimum r-squared threshold to report. Default: 0.05. Set higher (e.g., 0.8) for strong LD only.", "type": [ "number", "null" ] }, "variant_id": { "description": "rs ID of the variant. Examples: 'rs1042779', 'rs429358', 'rs7903146', 'rs6792369'.", "type": "string" } }, "required": [ "variant_id", "population" ], "type": "object" }