Cortexa research tool·genomics·ensembl_vep

EnsemblVEP Annotate Rsid

Predict functional consequences of a genetic variant using its dbSNP rs identifier via the Ensembl Variant Effect Predictor (VEP). Returns impact on genes, transcripts, and proteins including SIFT/PolyPhen scores, consequence types, amino acid changes, and colocated variants. Useful when you have a variant's rs number from GWAS, clinical reports, or literature. Example: 'rs7903146' (TCF7L2 T2D variant), 'rs429358' (APOE Alzheimer variant).

Livelast probed 2026-04-30 23:07Z· 120msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 120ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "rs_id": {
      "description": "Alias for variant_id. dbSNP rs identifier (e.g., 'rs7903146').",
      "type": "string"
    },
    "rsid": {
      "description": "Alias for variant_id. dbSNP rs identifier (e.g., 'rs7903146').",
      "type": "string"
    },
    "species": {
      "default": "human",
      "description": "Species name. Default: 'human'.",
      "type": "string"
    },
    "variant_id": {
      "description": "dbSNP rs identifier. Examples: 'rs7903146' (TCF7L2, type 2 diabetes), 'rs429358' (APOE, Alzheimer's), 'rs1801133' (MTHFR C677T). Aliases: rsid, rs_id.",
      "type": "string"
    }
  },
  "required": [],
  "type": "object"
}

Examples (1)

Default EnsemblVEP Annotate Rsid call

public-safeinput

{
  "rsid": "rs12345"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_EnsemblVEP_annotate_rsid
Tool name: EnsemblVEP_annotate_rsid
Added: 2026-04-30 22:47Z
Tags: tooluniverse

EnsemblVEP Annotate Rsid

Livelast probed 2026-04-30 23:07Z· 120msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "rs_id": { "description": "Alias for variant_id. dbSNP rs identifier (e.g., 'rs7903146').", "type": "string" }, "rsid": { "description": "Alias for variant_id. dbSNP rs identifier (e.g., 'rs7903146').", "type": "string" }, "species": { "default": "human", "description": "Species name. Default: 'human'.", "type": "string" }, "variant_id": { "description": "dbSNP rs identifier. Examples: 'rs7903146' (TCF7L2, type 2 diabetes), 'rs429358' (APOE, Alzheimer's), 'rs1801133' (MTHFR C677T). Aliases: rsid, rs_id.", "type": "string" } }, "required": [], "type": "object" }