IEDB Predict Mhci Binding

Predict MHC class I peptide binding using NetMHCpan via the IEDB Analysis Resource API. Given a protein sequence and HLA allele, predicts which peptides will bind and be presented on the cell surface. Returns peptides ranked by percentile rank (lower = stronger binding). Essential for vaccine design, neoantigen prediction, and epitope mapping. Supports human HLA-A/B/C and mouse H-2 alleles.