Cortexa research tool·genomics·mavedb

MaveDB Get Variant Scores

Get functional variant effect scores from a MaveDB score set. Returns HGVS-annotated variants with their functional scores from deep mutational scanning or other MAVE assays. Scores indicate variant effect on protein function (interpretation depends on the specific assay - check score set metadata). Optionally filter by HGVS protein notation (e.g., 'Arg175' to find all R175 substitutions).

Livelast probed 2026-04-30 23:07Z· 91msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 91ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "hgvs_pro": {
      "description": "Optional filter: HGVS protein notation substring (e.g., 'Arg175', 'p.Arg175His'). Case-insensitive partial match on protein-level HGVS.",
      "type": "string"
    },
    "limit": {
      "default": 50,
      "description": "Maximum variants to return (default 50, max 500).",
      "type": "integer"
    },
    "urn": {
      "description": "MaveDB score set URN (e.g., 'urn:mavedb:00001234-c-1'). Obtain from MaveDB_search_score_sets.",
      "type": "string"
    }
  },
  "required": [
    "urn"
  ],
  "type": "object"
}

Examples (1)

Default MaveDB Get Variant Scores call

public-safeinput

{
  "limit": 3,
  "urn": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_MaveDB_get_variant_scores
Tool name: MaveDB_get_variant_scores
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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