MaveDB Get Variant Scores
Get functional variant effect scores from a MaveDB score set. Returns HGVS-annotated variants with their functional scores from deep mutational scanning or other MAVE assays. Scores indicate variant effect on protein function (interpretation depends on the specific assay - check score set metadata). Optionally filter by HGVS protein notation (e.g., 'Arg175' to find all R175 substitutions). The /scores endpoint returns every variant in one CSV; `limit` is client-side truncation only — set `limit…
Overview
Get functional variant effect scores from a MaveDB score set. Returns HGVS-annotated variants with their functional scores from deep mutational scanning or other MAVE assays. Scores indicate variant effect on protein function (interpretation depends on the specific assay - check score set metadata). Optionally filter by HGVS protein notation (e.g., 'Arg175' to find all R175 substitutions). The /scores endpoint returns every variant in one CSV; `limit` is client-side truncation only — set `limit=0` (or omit) to receive ALL variants in one call (use this for whole-protein DMS analyses, e.g. KRAS folding ΔΔG has ~2200 variants).
Schema
JSON Schema the agent (or your API call) must match.
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Examples (1)
Default MaveDB Get Variant Scores call
Public-safe example · rate-limited
Identifiers
- Catalog ID
- tu_MaveDB_get_variant_scores
- Tool name
- MaveDB_get_variant_scores
- Added
- 2026-04-30 22:47Z
- Tags
- tooluniverse