Cortexa research tool·chemistry·metaboanalyst

MetaboAnalyst Pathway Enrichment

Perform metabolite pathway enrichment analysis (over-representation analysis) using hypergeometric test. Maps metabolite names to KEGG compound IDs, then tests which KEGG metabolic pathways are statistically enriched for the input metabolites. Returns pathways ranked by p-value with fold enrichment, FDR correction, and hit metabolites. Use for: identifying dysregulated metabolic pathways from a list of differentially abundant metabolites.

Livelast probed 2026-04-30 23:07Z· 2402msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 2402ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "metabolites": {
      "description": "List of metabolite names to test for pathway enrichment. Example: ['glucose', 'pyruvate', 'lactate', 'alanine', 'glycine']",
      "items": {
        "type": "string"
      },
      "type": "array"
    },
    "organism": {
      "description": "KEGG organism code. Default 'hsa' (human). Common: hsa=human, mmu=mouse, rno=rat, dme=fly, sce=yeast, eco=E.coli.",
      "type": "string"
    }
  },
  "required": [
    "metabolites"
  ],
  "type": "object"
}

Examples (1)

Default MetaboAnalyst Pathway Enrichment call

public-safeinput

{
  "metabolites": []
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_MetaboAnalyst_pathway_enrichment
Tool name: MetaboAnalyst_pathway_enrichment
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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