Cortexa research tool·genomics·oma

OMA Get Orthologs

Get pairwise orthologs for a protein from the OMA (Orthologous MAtrix) Browser. Returns orthologous proteins across species with relationship type (1:1, 1:many, many:1, many:many), evolutionary distance, and alignment score. OMA orthologs are inferred using a rigorous algorithm that provides high-confidence predictions. Example: P04637 (human p53) returns orthologs in 200+ species including Mus musculus, Danio rerio, and Drosophila melanogaster.

Livelast probed 2026-05-01 01:00Z· 95msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 95ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "per_page": {
      "description": "Number of orthologs to return (default: 20, max: 100).",
      "type": [
        "integer",
        "null"
      ]
    },
    "protein_id": {
      "description": "UniProt accession (e.g., 'P04637' for human p53) or OMA ID.",
      "type": "string"
    },
    "rel_type": {
      "description": "Filter by orthology relationship type. Options: '1:1' (one-to-one), '1:n' (one-to-many), 'n:1' (many-to-one), 'n:m' (many-to-many). Leave empty for all types.",
      "type": [
        "string",
        "null"
      ]
    }
  },
  "required": [
    "protein_id"
  ],
  "type": "object"
}

Examples (1)

Default OMA Get Orthologs call

public-safeinput

{
  "protein_id": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_OMA_get_orthologs
Tool name: OMA_get_orthologs
Added: 2026-05-01 00:58Z
Tags: tooluniverse

OMA Get Orthologs

Livelast probed 2026-05-01 01:00Z· 95msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "per_page": { "description": "Number of orthologs to return (default: 20, max: 100).", "type": [ "integer", "null" ] }, "protein_id": { "description": "UniProt accession (e.g., 'P04637' for human p53) or OMA ID.", "type": "string" }, "rel_type": { "description": "Filter by orthology relationship type. Options: '1:1' (one-to-one), '1:n' (one-to-many), 'n:1' (many-to-one), 'n:m' (many-to-many). Leave empty for all types.", "type": [ "string", "null" ] } }, "required": [ "protein_id" ], "type": "object" }