OmniPath Get Signaling Interactions
Get intracellular signaling pathway interactions from OmniPath's curated datasets. Supports querying the main OmniPath signaling network (literature-curated, directed PPI), pathwayextra (activity flow from Reactome/KEGG/WikiPathways), kinaseextra (kinase-substrate from PhosphoSite/dbPTM), and more. Returns directed, signed interactions with stimulation/inhibition annotations and supporting evidence. Useful for reconstructing signaling cascades downstream of receptor activation. Example: NOTCH1…
Overview
Get intracellular signaling pathway interactions from OmniPath's curated datasets. Supports querying the main OmniPath signaling network (literature-curated, directed PPI), pathwayextra (activity flow from Reactome/KEGG/WikiPathways), kinaseextra (kinase-substrate from PhosphoSite/dbPTM), and more. Returns directed, signed interactions with stimulation/inhibition annotations and supporting evidence. Useful for reconstructing signaling cascades downstream of receptor activation. Example: NOTCH1 has 110 directed signaling interactions; SRC kinase connects to 200+ downstream substrates; TP53 has 500+ pathway interactions.
Schema
JSON Schema the agent (or your API call) must match.
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Examples (1)
Default OmniPath Get Signaling Interactions call
Public-safe example · rate-limited
Identifiers
- Catalog ID
- tu_OmniPath_get_signaling_interactions
- Tool name
- OmniPath_get_signaling_interactions
- Added
- 2026-05-01 00:58Z
- Tags
- tooluniverse