Cortexa research tool·structure·Structural Biology

PDBePISA Get Interfaces

Analyze protein-protein and protein-ligand interfaces in a crystal structure using PDBePISA. Returns interface area, solvation energy, p-value, hydrogen bonds, salt bridges, disulfide bonds, and per-molecule contributions for each interface. Use after retrieving a PDB structure from RCSB/PDBe tools to assess biological relevance of crystal contacts. Low p-value (<0.5) and negative solvation energy suggest biologically relevant interfaces.

Livelast probed 2026-04-30 23:07Z· 109msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 109ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "pdb_id": {
      "description": "PDB entry ID (4-character code, e.g., '4hhb' for hemoglobin, '1cbs' for CRABP-II)",
      "type": "string"
    }
  },
  "required": [
    "pdb_id"
  ],
  "type": "object"
}

Examples (1)

Default PDBePISA Get Interfaces call

public-safeinput

{
  "pdb_id": "1AKI"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_PDBePISA_get_interfaces
Tool name: PDBePISA_get_interfaces
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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