Cortexa research tool·structure·prosite

PROSITE Scan Sequence

Scan a raw protein amino acid sequence against all PROSITE patterns and profiles to find matching motifs and domains. Returns PROSITE signature accessions, names, positions, and confidence scores. This is the sequence-based alternative to ScanProsite_scan_protein (which accepts UniProt accessions). Use this when you have a novel or modified sequence not in UniProt. By default, skips frequent/low-information patterns (like N-glycosylation); set skip_frequent=false to include all matches.

Livelast probed 2026-04-30 23:07Z· 115msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 115ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "sequence": {
      "description": "Protein amino acid sequence in single-letter code (e.g., 'MKTAYIAKQRQ...'). Must contain only standard amino acid letters.",
      "type": "string"
    },
    "skip_frequent": {
      "description": "If true (default), skip frequent low-information patterns like glycosylation sites. Set to false to include all matches.",
      "type": "boolean"
    }
  },
  "required": [
    "sequence"
  ],
  "type": "object"
}

Examples (1)

Default PROSITE Scan Sequence call

public-safeinput

{
  "sequence": "",
  "skip_frequent": false
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_PROSITE_scan_sequence
Tool name: PROSITE_scan_sequence
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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