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Cortexa research tool·structure·proteinsplus

ProteinsPlus Predict Binding Sites V3

Predict druggable binding sites using DoGSite3 algorithm with ligand-biased grid option. Enhanced version of DoGSiteScorer with improved binding site detection. Input can be a PDB ID with optional reference ligand for biased grid calculations. Returns predicted pockets with druggability scores, geometric properties, and detailed subpocket analysis. Supports ligand-based grid biasing to focus predictions around known binding sites. Useful for comprehensive binding site characterization and struc…

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Overview

Predict druggable binding sites using DoGSite3 algorithm with ligand-biased grid option. Enhanced version of DoGSiteScorer with improved binding site detection. Input can be a PDB ID with optional reference ligand for biased grid calculations. Returns predicted pockets with druggability scores, geometric properties, and detailed subpocket analysis. Supports ligand-based grid biasing to focus predictions around known binding sites. Useful for comprehensive binding site characterization and structure-based drug design workflows. Example: Analyze 1KZK with ligand JE2_A_701 to identify druggable sites near the co-crystallized ligand.

Schema

JSON Schema the agent (or your API call) must match.

JSON · 40 lines · 1,488 chars

Examples (1)

Default ProteinsPlus Predict Binding Sites V3 call

public-safeinput
JSON · 4 lines · 46 chars
Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID
tu_ProteinsPlus_predict_binding_sites_v3
Tool name
ProteinsPlus_predict_binding_sites_v3
Added
2026-04-30 22:47Z
Tags
tooluniverse
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