Cortexa research tool·structure·string_ext

STRING Get Enrichment

Perform functional enrichment analysis on a set of proteins using the STRING database. Tests whether the input protein list is statistically enriched for Gene Ontology terms, KEGG pathways, Reactome pathways, WikiPathways, InterPro domains, TISSUES, DISEASES, COMPARTMENTS, and other functional categories. Returns enriched terms with p-values, FDR-corrected q-values, and the matching proteins. Useful for interpreting gene lists from RNA-seq, GWAS, proteomics experiments.

Livelast probed 2026-04-30 23:07Z· 98msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 98ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "background_string_identifiers": {
      "description": "Optional newline-separated background gene set. If not provided, the entire genome proteome is used as background.",
      "type": [
        "string",
        "null"
      ]
    },
    "identifiers": {
      "description": "Newline-separated list of protein identifiers (gene names or STRING IDs). Example: 'BRCA1\\nBRCA2\\nTP53\\nATM'. Minimum 2 proteins, recommended 5-100 for meaningful enrichment.",
      "type": "string"
    },
    "species": {
      "default": 9606,
      "description": "NCBI taxonomy ID (default 9606 for human). Examples: 9606 (human), 10090 (mouse), 7227 (fly), 6239 (worm).",
      "type": "integer"
    }
  },
  "required": [
    "identifiers"
  ],
  "type": "object"
}

Examples (1)

Default STRING Get Enrichment call

public-safeinput

{
  "identifiers": "",
  "species": 1
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_STRING_get_enrichment
Tool name: STRING_get_enrichment
Added: 2026-04-30 22:47Z
Tags: tooluniverse

STRING Get Enrichment

Livelast probed 2026-04-30 23:07Z· 98msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "background_string_identifiers": { "description": "Optional newline-separated background gene set. If not provided, the entire genome proteome is used as background.", "type": [ "string", "null" ] }, "identifiers": { "description": "Newline-separated list of protein identifiers (gene names or STRING IDs). Example: 'BRCA1\\nBRCA2\\nTP53\\nATM'. Minimum 2 proteins, recommended 5-100 for meaningful enrichment.", "type": "string" }, "species": { "default": 9606, "description": "NCBI taxonomy ID (default 9606 for human). Examples: 9606 (human), 10090 (mouse), 7227 (fly), 6239 (worm).", "type": "integer" } }, "required": [ "identifiers" ], "type": "object" }