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Cortexa research tool·genomics·HumanBase
Humanbase Ppi Analysis
Retrieve tissue-specific protein-protein interactions and biological processes from HumanBase. Returns a NetworkX graph of tissue specific protein-protein interactions and a list of associated biological processes involeed by the given genes from Gene Ontology.
Livelast probed 2026-04-30 23:07Z· 1263msCortexa
Status
The most recent probe succeeded. Safe to call from the agent today.
- Last probed
- 1d ago
- Last success
- 1d ago
- Last latency
- 1263ms
Schema
JSON Schema the agent (or your API call) must match.
{
"properties": {
"gene_list": {
"description": "List of gene names or symbols to analyze for protein-protein interactions. The gene name should be the official gene symbol, not the synonym.",
"items": {
"type": "string"
},
"minItems": 1,
"type": "array"
},
"genes": {
"description": "Alias for gene_list. List of gene symbols to analyze.",
"items": {
"type": "string"
},
"type": "array"
},
"interaction": {
"description": "Specific interaction type to filter by. Available types: 'co-expression', 'interaction', 'tf-binding', 'gsea-microrna-targets', 'gsea-perturbations'. If not specified, all types will be included.",
"enum": [
"co-expression",
"interaction",
"tf-binding",
"gsea-microrna-targets",
"gsea-perturbations"
],
"type": "string"
},
"max_node": {
"default": 10,
"description": "Maximum number of nodes to retrieve in the interaction network. Warning: the more nodes, the more time it takes to retrieve the data. Default is 10 (~30 seconds).",
"maximum": 100,
"minimum": 1,
"type": "integer"
},
"string_mode": {
"default": true,
"description": "Whether to return the result in string mode. If True, the result will be a string of the network graph and the biological processes. If False, the result will be a NetworkX graph and a list of biological processes.",
"type": "boolean"
},
"tissue": {
"default": "brain",
"description": "Tissue type for tissue-specific interactions. Use simple names like 'brain', 'heart', 'liver', 'kidney', 'lung', 'blood'. For v3 networks with more cell-type specificity, append '-v3' (e.g., 'brain-v3', 'liver-v3').",
"type": "string"
},
"top_n": {
"description": "Alias for max_node. Maximum number of network nodes to retrieve.",
"maximum": 100,
"minimum": 1,
"type": "integer"
}
},
"required": [],
"type": "object"
}Examples (1)
Default Humanbase Ppi Analysis call
public-safeinput
{
"gene_list": [],
"genes": [],
"max_node": 1,
"string_mode": false,
"top_n": 1
}Expected response keys: success
Anonymous-safe example. Rate-limited; no sign-in required.
Identifiers
- Catalog ID
- tu_humanbase_ppi_analysis
- Tool name
- humanbase_ppi_analysis
- Added
- 2026-04-30 22:47Z
- Tags
- tooluniverse