APPRIS Get Functional Annotations

Get detailed functional annotations for gene isoforms from APPRIS, including structural domains (spade), functional residues (firestar), 3D structure coverage (matador3d), cross-species conservation (corsair), transmembrane helices (thump), signal peptides (crash), and proteomics evidence (proteo). Annotations are grouped by type. Optionally filter by transcript_id to focus on a specific isoform. Available methods: appris, firestar, matador3d, spade, corsair, thump, crash, proteo, tsl