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Research tool·structure·alphafill

AlphaFill Get Transplants

Get the ligands, cofactors, and ions that AlphaFill transplants into a protein's AlphaFold model, by UniProt accession. AlphaFold predicts apo (ligand-free) structures; AlphaFill adds small molecules by homology to experimental PDB structures. Returns the distinct transplanted compounds (PDB chemical-component codes), how many homologous hits support each, the best local fit RMSD (lower = better), and the source PDB entries. Use to hypothesize cofactor/metal/ligand/drug binding for a protein wh…

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Overview

Get the ligands, cofactors, and ions that AlphaFill transplants into a protein's AlphaFold model, by UniProt accession. AlphaFold predicts apo (ligand-free) structures; AlphaFill adds small molecules by homology to experimental PDB structures. Returns the distinct transplanted compounds (PDB chemical-component codes), how many homologous hits support each, the best local fit RMSD (lower = better), and the source PDB entries. Use to hypothesize cofactor/metal/ligand/drug binding for a protein whose only structure is an AlphaFold model. No API key required.

Schema

JSON Schema the agent (or your API call) must match.

JSON · 12 lines · 225 chars

Examples (1)

Default AlphaFill Get Transplants call

public-safeinput
JSON · 3 lines · 25 chars
Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID
tu_AlphaFill_get_transplants
Tool name
AlphaFill_get_transplants
Added
2026-07-29 18:13Z
Tags
tooluniverse
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