BRENDA Get Enzyme Kinetics

Overview

Get comprehensive enzyme kinetic parameters WITHOUT requiring BRENDA credentials. Retrieves enzyme identity (name, catalytic activity, alternative names) from ExPASy ENZYME and kinetic parameters (Km, kcat, Ki, Vmax, kcat/Km) from SABIO-RK. If BRENDA credentials are set (BRENDA_EMAIL, BRENDA_PASSWORD), additionally fetches optimal pH, optimal temperature, and specific activity from BRENDA. Accepts EC number (e.g., 1.1.1.1) or enzyme name (e.g., alcohol dehydrogenase). Returns aggregated summary statistics across all reported values plus individual measurements with substrate specificity and organism information.

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed

1d ago

Last success

1d ago

Last latency

105ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "ec_number": {
      "description": "EC number (e.g., 1.1.1.1 for alcohol dehydrogenase, 2.7.1.1 for hexokinase, 3.4.21.5 for thrombin)",
      "type": "string"
    },
    "enzyme_id": {
      "description": "Alias for ec_number. Enzyme identifier in EC notation.",
      "type": "string"
    },
    "enzyme_name": {
      "description": "Enzyme common name. Will be resolved to EC number via UniProt. Examples: alcohol dehydrogenase, hexokinase, lactate dehydrogenase, thrombin",
      "type": "string"
    },
    "limit": {
      "description": "Maximum number of SABIO-RK kinetic law entries to retrieve (default 20)",
      "type": [
        "integer",
        "null"
      ]
    },
    "operation": {
      "const": "get_enzyme_kinetics",
      "description": "Operation type (fixed: get_enzyme_kinetics)",
      "type": "string"
    },
    "organism": {
      "description": "Optional organism filter (e.g., Homo sapiens, Escherichia coli, Saccharomyces cerevisiae)",
      "type": "string"
    }
  },
  "required": [],
  "type": "object"
}

Examples (1)

{}

Identifiers

Catalog ID

tu_BRENDA_get_enzyme_kinetics

Tool name

BRENDA_get_enzyme_kinetics

Added

2026-05-01 00:58Z

Tags

tooluniverse