Cortexa research tool·drug discovery·ChEMBL

ChEMBL Search Activities

Search activity data by molecule, target, assay, or activity values. Supports filtering by IC50, Ki, EC50, etc. Note: activity data is sparse and depends on curation; some specific filter combinations can legitimately return zero results. For reliable retrieval, prefer starting from a known target (`target_chembl_id__exact`) or assay (`assay_chembl_id__exact`). To find molecule or target IDs, use ChEMBL_search_molecules or ChEMBL_search_targets.

Livelast probed 2026-04-30 23:07Z· 1792msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 1792ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "assay_chembl_id": {
      "description": "Filter by assay ChEMBL ID",
      "type": "string"
    },
    "fields": {
      "description": "Optional list of ChEMBL activity fields to include in each returned activity object (projection). Cortexa Tool Mesh maps this to ChEMBL's `only` query parameter (comma-separated). Supported fields: activity_id, molecule_chembl_id, target_chembl_id, assay_chembl_id, standard_type, standard_value, standard_units, pchembl_value, standard_relation, standard_flag.",
      "items": {
        "enum": [
          "activity_id",
          "molecule_chembl_id",
          "target_chembl_id",
          "assay_chembl_id",
          "standard_type",
          "standard_value",
          "standard_units",
          "pchembl_value",
          "standard_relation",
          "standard_flag"
        ],
        "type": "string"
      },
      "type": "array",
      "uniqueItems": true
    },
    "limit": {
      "default": 20,
      "maximum": 1000,
      "type": "integer"
    },
    "molecule_chembl_id": {
      "description": "Filter by molecule ChEMBL ID",
      "type": "string"
    },
    "offset": {
      "default": 0,
      "type": "integer"
    },
    "standard_type": {
      "description": "Filter by activity type (e.g., 'IC50', 'Ki', 'EC50')",
      "type": "string"
    },
    "standard_value__gte": {
      "description": "Filter by minimum activity value",
      "type": "number"
    },
    "standard_value__lte": {
      "description": "Filter by maximum activity value",
      "type": "number"
    },
    "target_chembl_id": {
      "description": "Filter by target ChEMBL ID",
      "type": "string"
    }
  },
  "required": [],
  "type": "object"
}

Examples (1)

Default ChEMBL Search Activities call

public-safeinput

{
  "fields": [],
  "limit": 3,
  "offset": 1,
  "standard_value__gte": 1,
  "standard_value__lte": 1
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_ChEMBL_search_activities
Tool name: ChEMBL_search_activities
Added: 2026-04-30 22:47Z
Tags: tooluniverse

ChEMBL Search Activities

Livelast probed 2026-04-30 23:07Z· 1792msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "assay_chembl_id": { "description": "Filter by assay ChEMBL ID", "type": "string" }, "fields": { "description": "Optional list of ChEMBL activity fields to include in each returned activity object (projection). Cortexa Tool Mesh maps this to ChEMBL's `only` query parameter (comma-separated). Supported fields: activity_id, molecule_chembl_id, target_chembl_id, assay_chembl_id, standard_type, standard_value, standard_units, pchembl_value, standard_relation, standard_flag.", "items": { "enum": [ "activity_id", "molecule_chembl_id", "target_chembl_id", "assay_chembl_id", "standard_type", "standard_value", "standard_units", "pchembl_value", "standard_relation", "standard_flag" ], "type": "string" }, "type": "array", "uniqueItems": true }, "limit": { "default": 20, "maximum": 1000, "type": "integer" }, "molecule_chembl_id": { "description": "Filter by molecule ChEMBL ID", "type": "string" }, "offset": { "default": 0, "type": "integer" }, "standard_type": { "description": "Filter by activity type (e.g., 'IC50', 'Ki', 'EC50')", "type": "string" }, "standard_value__gte": { "description": "Filter by minimum activity value", "type": "number" }, "standard_value__lte": { "description": "Filter by maximum activity value", "type": "number" }, "target_chembl_id": { "description": "Filter by target ChEMBL ID", "type": "string" } }, "required": [], "type": "object" }