Cortexa research tool·drug discovery·dgidb

DGIdb Get Drug Gene Interactions

Get drug-gene interactions for a list of genes from DGIdb. Returns drugs targeting each gene, interaction types, and evidence sources.

Livelast probed 2026-04-30 23:07Z· 104msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 104ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "gene": {
      "description": "Alias for genes. Single gene symbol (e.g., 'EGFR').",
      "type": "string"
    },
    "gene_name": {
      "description": "Alias for genes. Single gene symbol (e.g., 'EGFR').",
      "type": "string"
    },
    "genes": {
      "description": "List of gene symbols (e.g., ['EGFR', 'BRAF']). Also accepts a single gene as string. Aliases: gene_name, gene.",
      "items": {
        "type": "string"
      },
      "type": "array"
    },
    "interaction_sources": {
      "description": "Optional filter by data sources (e.g., ['DrugBank', 'ChEMBL']).",
      "items": {
        "type": "string"
      },
      "type": "array"
    },
    "interaction_types": {
      "description": "Optional filter by interaction types (e.g., ['inhibitor', 'antagonist']).",
      "items": {
        "type": "string"
      },
      "type": "array"
    }
  },
  "required": [],
  "type": "object"
}

Examples (1)

Default DGIdb Get Drug Gene Interactions call

public-safeinput

{
  "gene": "BRCA1",
  "gene_name": "BRCA1",
  "genes": [],
  "interaction_sources": [],
  "interaction_types": []
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_DGIdb_get_drug_gene_interactions
Tool name: DGIdb_get_drug_gene_interactions
Added: 2026-04-30 22:47Z
Tags: tooluniverse

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "gene": { "description": "Alias for genes. Single gene symbol (e.g., 'EGFR').", "type": "string" }, "gene_name": { "description": "Alias for genes. Single gene symbol (e.g., 'EGFR').", "type": "string" }, "genes": { "description": "List of gene symbols (e.g., ['EGFR', 'BRAF']). Also accepts a single gene as string. Aliases: gene_name, gene.", "items": { "type": "string" }, "type": "array" }, "interaction_sources": { "description": "Optional filter by data sources (e.g., ['DrugBank', 'ChEMBL']).", "items": { "type": "string" }, "type": "array" }, "interaction_types": { "description": "Optional filter by interaction types (e.g., ['inhibitor', 'antagonist']).", "items": { "type": "string" }, "type": "array" } }, "required": [], "type": "object" }