Cortexa research tool·genomics·dna_tools

DNA Codon Optimize

Codon-optimize an amino acid sequence for expression in a target species (human, ecoli, mouse, or yeast) using species-specific codon frequency tables. Returns the optimized DNA sequence, GC content, Codon Adaptation Index (CAI), and sequence length. Use for: synthetic gene design, heterologous protein expression, improving codon usage for a target host organism.

Livelast probed 2026-04-30 23:07Z· 101msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 101ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "operation": {
      "description": "Operation type",
      "enum": [
        "codon_optimize"
      ],
      "type": "string"
    },
    "sequence": {
      "description": "Amino acid sequence in single-letter code (e.g., 'MEPVDDLPL'). Stop codon (*) is optional at the end.",
      "type": "string"
    },
    "species": {
      "default": "human",
      "description": "Target expression organism. Options: 'human' (default), 'ecoli', 'mouse', 'yeast'.",
      "enum": [
        "human",
        "ecoli",
        "mouse",
        "yeast",
        null
      ],
      "type": [
        "string",
        "null"
      ]
    }
  },
  "required": [
    "operation",
    "sequence"
  ],
  "type": "object"
}

Examples (1)

Default DNA Codon Optimize call

public-safeinput

{
  "operation": "",
  "sequence": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_DNA_codon_optimize
Tool name: DNA_codon_optimize
Added: 2026-04-30 22:47Z
Tags: tooluniverse

DNA Codon Optimize

Livelast probed 2026-04-30 23:07Z· 101msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "operation": { "description": "Operation type", "enum": [ "codon_optimize" ], "type": "string" }, "sequence": { "description": "Amino acid sequence in single-letter code (e.g., 'MEPVDDLPL'). Stop codon (*) is optional at the end.", "type": "string" }, "species": { "default": "human", "description": "Target expression organism. Options: 'human' (default), 'ecoli', 'mouse', 'yeast'.", "enum": [ "human", "ecoli", "mouse", "yeast", null ], "type": [ "string", "null" ] } }, "required": [ "operation", "sequence" ], "type": "object" }