DoseResponse Calculate Ic50
Determine the half-maximal inhibitory or effective concentration (IC50/EC50) from paired concentration-response data by fitting the Hill sigmoidal equation. Requires a minimum of 4 data points that span the dynamic response range. Output includes EC50 with 95% confidence interval, Hill exponent n, top plateau Emax, bottom plateau Emin, R2 goodness-of-fit, and log10(EC50) for convenient pIC50 conversion. Suited to potency ranking in compound screens, structure-activity relationship analysis, and…
Overview
Determine the half-maximal inhibitory or effective concentration (IC50/EC50) from paired concentration-response data by fitting the Hill sigmoidal equation. Requires a minimum of 4 data points that span the dynamic response range. Output includes EC50 with 95% confidence interval, Hill exponent n, top plateau Emax, bottom plateau Emin, R2 goodness-of-fit, and log10(EC50) for convenient pIC50 conversion. Suited to potency ranking in compound screens, structure-activity relationship analysis, and cross-assay comparisons.
Schema
JSON Schema the agent (or your API call) must match.
Examples (1)
Default DoseResponse Calculate Ic50 call
Anonymous-safe example. Rate-limited; no sign-in required.
Identifiers
- Catalog ID
- tu_DoseResponse_calculate_ic50
- Tool name
- DoseResponse_calculate_ic50
- Added
- 2026-04-30 22:47Z
- Tags
- tooluniverse