DoseResponse Compare Potency

Quantify relative potency between two compounds by independently fitting Hill sigmoidal curves to each concentration-response dataset and computing the EC50 fold-shift (compound B EC50 / compound A EC50). Reports EC50, Hill exponent, and plateau Emax per compound, the potency fold-ratio, and which compound is more potent. Applications include lead optimisation, matched-pair structure-activity analysis, and selectivity profiling.