CapabilitiesIntegrationsDocsCatalogPricing
Sign In
Start research
Back to catalog
Cortexa research tool·drug discovery·dose_response

DoseResponse Fit Curve

Nonlinear regression of paired concentration-response measurements to the Hill sigmoidal (4PL) model: f(x) = Emin + (Emax - Emin) / (1 + (EC50/x)^n). Returns the four fitted parameters (baseline Emin, plateau Emax, midpoint EC50, Hill exponent n) with standard errors, 95% CI for EC50, coefficient of determination R2, and predicted response at each measured concentration. Requires at least 4 positive concentration inputs. Useful for characterising pharmacological potency and assessing assay data…

AvailableCortexa

Overview

Nonlinear regression of paired concentration-response measurements to the Hill sigmoidal (4PL) model: f(x) = Emin + (Emax - Emin) / (1 + (EC50/x)^n). Returns the four fitted parameters (baseline Emin, plateau Emax, midpoint EC50, Hill exponent n) with standard errors, 95% CI for EC50, coefficient of determination R2, and predicted response at each measured concentration. Requires at least 4 positive concentration inputs. Useful for characterising pharmacological potency and assessing assay data quality.

Schema

JSON Schema the agent (or your API call) must match.

JSON · 31 lines · 739 chars

Examples (1)

Default DoseResponse Fit Curve call

public-safeinput
JSON · 5 lines · 64 chars
Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID
tu_DoseResponse_fit_curve
Tool name
DoseResponse_fit_curve
Added
2026-05-01 00:58Z
Tags
tooluniverse
Cortexa.

The agent for research teams. 2.2K+ verified tools across every research discipline, every claim cited.

Product

  • Capabilities
  • Integrations
  • Documentation
  • Tool catalog
  • Pricing

Get started

  • Launch the agent
  • Sign in
  • Developer API
  • MCP server

Support

  • Help center
  • Contact us
  • Terms of Service
  • Privacy Policy

© 2026 Cortexa. All rights reserved.

TermsPrivacy·For research context only · Not medical, legal, or financial advice.