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Cortexa research tool·chemistry·drug_properties

DrugProps Calculate Qed

Calculate Quantitative Estimate of Drug-likeness (QED) score for a compound using the Bickerton et al. (2012) method. QED integrates 8 molecular descriptors (MW, AlogP, HBA, HBD, PSA, rotatable bonds, aromatic rings, structural alerts) into a single score from 0 (non-drug-like) to 1 (most drug-like). Median QED of approved oral drugs is ~0.49. High QED (≥0.67) = drug-like; Medium (0.34–0.67) = borderline; Low (<0.34) = non-drug-like. Use after DrugProps_lipinski_filter for a more nuanced drug-l…

AvailableCortexa

Overview

Calculate Quantitative Estimate of Drug-likeness (QED) score for a compound using the Bickerton et al. (2012) method. QED integrates 8 molecular descriptors (MW, AlogP, HBA, HBD, PSA, rotatable bonds, aromatic rings, structural alerts) into a single score from 0 (non-drug-like) to 1 (most drug-like). Median QED of approved oral drugs is ~0.49. High QED (≥0.67) = drug-like; Medium (0.34–0.67) = borderline; Low (<0.34) = non-drug-like. Use after DrugProps_lipinski_filter for a more nuanced drug-likeness assessment.

Schema

JSON Schema the agent (or your API call) must match.

JSON · 12 lines · 288 chars

Examples (1)

Default DrugProps Calculate Qed call

public-safeinput
JSON · 3 lines · 39 chars
Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID
tu_DrugProps_calculate_qed
Tool name
DrugProps_calculate_qed
Added
2026-04-30 22:47Z
Tags
tooluniverse
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