DrugSynergy Calculate Ci
Calculate Chou-Talalay Combination Index (CI) for drug synergy quantification. CI is derived from the Median Effect Equation: fa/fu = (D/Dm)^m. CI < 1 indicates synergy, CI = 1 is additive, CI > 1 is antagonism. Also computes the Dose Reduction Index (DRI) showing how much each drug dose can be reduced in combination. Supports both mutually exclusive (drugs with similar mechanisms) and mutually non-exclusive (drugs with different mechanisms) assumptions. Based on Chou & Talalay (1984). Use for:…
Overview
Calculate Chou-Talalay Combination Index (CI) for drug synergy quantification. CI is derived from the Median Effect Equation: fa/fu = (D/Dm)^m. CI < 1 indicates synergy, CI = 1 is additive, CI > 1 is antagonism. Also computes the Dose Reduction Index (DRI) showing how much each drug dose can be reduced in combination. Supports both mutually exclusive (drugs with similar mechanisms) and mutually non-exclusive (drugs with different mechanisms) assumptions. Based on Chou & Talalay (1984). Use for: quantitative synergy assessment, dose optimization, isobologram analysis.
Schema
JSON Schema the agent (or your API call) must match.
Examples (1)
Default DrugSynergy Calculate Ci call
Anonymous-safe example. Rate-limited; no sign-in required.
Identifiers
- Catalog ID
- tu_DrugSynergy_calculate_ci
- Tool name
- DrugSynergy_calculate_ci
- Added
- 2026-05-01 00:58Z
- Tags
- tooluniverse