EBIProteins Get Variation By Hgvs
Reverse variation lookup by HGVS genomic expression from the EBI Proteins API. Given an HGVS genomic-level expression (e.g. 'NC_000017.11:g.7676154G>A'), returns every overlapping UniProt protein with the resulting variant consequence projected onto the protein sequence (wild-type and alternative residue, protein position, genomic location). Use to translate a genomic DNA change into its protein consequence across all affected UniProt entries. Example: 'NC_000017.11:g.7676154G>A' returns 4 UniP…
Overview
Reverse variation lookup by HGVS genomic expression from the EBI Proteins API. Given an HGVS genomic-level expression (e.g. 'NC_000017.11:g.7676154G>A'), returns every overlapping UniProt protein with the resulting variant consequence projected onto the protein sequence (wild-type and alternative residue, protein position, genomic location). Use to translate a genomic DNA change into its protein consequence across all affected UniProt entries. Example: 'NC_000017.11:g.7676154G>A' returns 4 UniProt entries; the TP53 (P04637) entry reports VARIANT P->L at residue 72 (the Pro72Leu protein consequence).
Schema
JSON Schema the agent (or your API call) must match.
Examples (1)
Default EBIProteins Get Variation By Hgvs call
Anonymous-safe example. Rate-limited; no sign-in required.
Identifiers
- Catalog ID
- tu_EBIProteins_get_variation_by_hgvs
- Tool name
- EBIProteins_get_variation_by_hgvs
- Added
- 2026-07-29 18:13Z
- Tags
- tooluniverse