Cortexa research tool·genomics·epigenomics

ENCODE Search Methylation Experiments

Search ENCODE whole-genome bisulfite sequencing (WGBS) and reduced-representation bisulfite sequencing (RRBS) experiments for DNA methylation profiling. Returns experiment accessions, biosample information, methylation assay type, and metadata. DNA methylation (5mC) at CpG sites is a key epigenetic mark regulating gene silencing, genomic imprinting, and X-inactivation. Use this to find methylation data for specific tissues, cell lines, or developmental stages.

Livelast probed 2026-05-01 01:00Z· 318msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 318ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "assay_type": {
      "default": "WGBS",
      "description": "Methylation assay type: 'WGBS' (whole-genome bisulfite sequencing, comprehensive CpG coverage) or 'RRBS' (reduced-representation, enriched for CpG islands).",
      "type": "string"
    },
    "biosample_term_name": {
      "description": "Biosample name filter (e.g., 'K562', 'liver', 'brain', 'motor neuron'). Leave empty for all.",
      "type": [
        "string",
        "null"
      ]
    },
    "limit": {
      "default": 25,
      "description": "Maximum number of results to return.",
      "maximum": 100,
      "minimum": 1,
      "type": "integer"
    },
    "organism": {
      "default": "Homo sapiens",
      "description": "Organism scientific name.",
      "type": "string"
    }
  },
  "type": "object"
}

Examples (1)

Default ENCODE Search Methylation Experiments call

public-safeinput

{
  "limit": 3
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_ENCODE_search_methylation_experiments
Tool name: ENCODE_search_methylation_experiments
Added: 2026-05-01 00:58Z
Tags: tooluniverse

ENCODE Search Methylation Experiments

Livelast probed 2026-05-01 01:00Z· 318msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "assay_type": { "default": "WGBS", "description": "Methylation assay type: 'WGBS' (whole-genome bisulfite sequencing, comprehensive CpG coverage) or 'RRBS' (reduced-representation, enriched for CpG islands).", "type": "string" }, "biosample_term_name": { "description": "Biosample name filter (e.g., 'K562', 'liver', 'brain', 'motor neuron'). Leave empty for all.", "type": [ "string", "null" ] }, "limit": { "default": 25, "description": "Maximum number of results to return.", "maximum": 100, "minimum": 1, "type": "integer" }, "organism": { "default": "Homo sapiens", "description": "Organism scientific name.", "type": "string" } }, "type": "object" }