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Research tool·genomics·ensembl_compara

EnsemblCompara Get Cafe Tree

Retrieve the Ensembl Compara CAFE tree for a gene family: the gene gain/loss (expansion/contraction) analysis that infers ancestral gene-copy counts (n_members) at every node of the species tree, with the birth-death rate (lambda) and per-node p-values. Unlike EnsemblCompara_get_gene_tree (which returns the phylogenetic gene tree topology + members), this returns the CAFE family-size dynamics used to detect lineage-specific gene-family expansions/contractions. Provide either gene_tree_id (e.g.…

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Overview

Retrieve the Ensembl Compara CAFE tree for a gene family: the gene gain/loss (expansion/contraction) analysis that infers ancestral gene-copy counts (n_members) at every node of the species tree, with the birth-death rate (lambda) and per-node p-values. Unlike EnsemblCompara_get_gene_tree (which returns the phylogenetic gene tree topology + members), this returns the CAFE family-size dynamics used to detect lineage-specific gene-family expansions/contractions. Provide either gene_tree_id (e.g. 'ENSGT00390000003602') or gene (symbol e.g. 'BRCA2', or Ensembl gene ID). Example: gene_tree_id='ENSGT00390000003602' returns type 'cafe tree', rooted, pvalue_avg, lambda ~5.08e-08, and per-node n_members / pvalue along the species tree.

Schema

JSON Schema the agent (or your API call) must match.

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JSON · 26 lines · 724 chars

Examples (1)

Default EnsemblCompara Get Cafe Tree call

Public-safe example · rate-limited

JSON input · 5 lines · 83 chars
Expected response keys: success

Identifiers

Catalog ID
tu_EnsemblCompara_get_cafe_tree
Tool name
EnsemblCompara_get_cafe_tree
Added
2026-07-29 18:13Z
Tags
tooluniverse
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