Cortexa research tool·drug discovery·epigraphdb

EpiGraphDB Get Drugs For Trait

Find drugs that target genes associated with a GWAS risk factor trait. Uses genetic evidence to identify drug repurposing candidates. Returns drugs whose target genes are significantly associated with the trait via GWAS. Example: 'LDL cholesterol' returns statins (targeting HMGCR), PCSK9 inhibitors, etc.

Livelast probed 2026-04-30 23:07Z· 116msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 116ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "pval_threshold": {
      "default": 0.0001,
      "description": "GWAS p-value threshold for gene-trait associations (default 1e-4).",
      "type": "number"
    },
    "trait": {
      "description": "GWAS risk factor trait name (e.g., 'LDL cholesterol', 'Body mass index', 'C-reactive protein', 'Systolic blood pressure').",
      "type": "string"
    }
  },
  "required": [
    "trait"
  ],
  "type": "object"
}

Examples (1)

Default EpiGraphDB Get Drugs For Trait call

public-safeinput

{
  "pval_threshold": 1,
  "trait": "type 2 diabetes"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_EpiGraphDB_get_drugs_for_trait
Tool name: EpiGraphDB_get_drugs_for_trait
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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