Cortexa research tool·genomics·epigraphdb

EpiGraphDB Get Genetic Correlations

Get genetic correlations (rg) between a GWAS trait and all other traits in the IEU OpenGWAS database. Returns traits with significant genetic overlap. Useful for understanding shared genetic architecture between diseases. Example: 'Body mass index' shows high genetic correlation with waist circumference, diabetes.

Livelast probed 2026-04-30 23:07Z· 108msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 108ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "pval_threshold": {
      "default": 0.05,
      "description": "P-value threshold for genetic correlations (default 0.05).",
      "type": "number"
    },
    "trait": {
      "description": "GWAS trait name to find genetic correlations for (e.g., 'Body mass index', 'Depression', 'Type 2 diabetes').",
      "type": "string"
    }
  },
  "required": [
    "trait"
  ],
  "type": "object"
}

Examples (1)

Default EpiGraphDB Get Genetic Correlations call

public-safeinput

{
  "pval_threshold": 1,
  "trait": "type 2 diabetes"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_EpiGraphDB_get_genetic_correlations
Tool name: EpiGraphDB_get_genetic_correlations
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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