GTEx Calculate Eqtl

Overview

Calculate custom eQTL for any gene-variant pair in any tissue. Dynamically calculates gene-variant association statistics including p-value, normalized effect size (NES), t-statistic, and genotype data. Works for both significant and non-significant associations. Returns detailed statistics even if association not in precomputed results. Use for: testing specific hypotheses, custom variant-gene pairs, dynamic eQTL analysis, validating findings. Requires all three: gencode_id, variant_id, and tissue_site_detail_id.

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed

1d ago

Last success

1d ago

Last latency

124ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "dataset_id": {
      "default": "gtex_v8",
      "enum": [
        "gtex_v8",
        "gtex_v10",
        "gtex_snrnaseq_pilot"
      ],
      "type": "string"
    },
    "gencode_id": {
      "description": "Required: Versioned GENCODE ID (e.g. ENSG00000141510.18)",
      "type": "string"
    },
    "operation": {
      "description": "Operation type",
      "enum": [
        "calculate_eqtl"
      ],
      "type": "string"
    },
    "tissue_site_detail_id": {
      "description": "Required: Tissue ID (e.g. 'Whole_Blood')",
      "type": "string"
    },
    "variant_id": {
      "description": "Required: GTEx variant ID",
      "type": "string"
    }
  },
  "required": [
    "gencode_id",
    "variant_id",
    "tissue_site_detail_id"
  ],
  "type": "object"
}

Examples (1)

{
  "gencode_id": "",
  "tissue_site_detail_id": "",
  "variant_id": ""
}

Identifiers

Catalog ID

tu_GTEx_calculate_eqtl

Tool name

GTEx_calculate_eqtl

Added

2026-04-30 22:47Z

Tags

tooluniverse