Cortexa research tool·genomics·gwas_sumstats

GWASSumStats Get Region Associations

Query full GWAS summary statistics for variants in a chromosomal region. Returns variant-level association data including p-values, effect sizes (beta/OR), allele frequencies, and study/trait information. Unlike gwas_search_associations (which returns curated top hits), this endpoint provides complete summary statistics from deposited studies. Filter by chromosome region, p-value threshold, and optionally by specific study.

Livelast probed 2026-04-30 23:07Z· 92msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 92ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "bp_lower": {
      "description": "Start position of the region (GRCh38 coordinates).",
      "type": "integer"
    },
    "bp_upper": {
      "description": "End position of the region (GRCh38 coordinates).",
      "type": "integer"
    },
    "chromosome": {
      "description": "Chromosome number (1-22, or 23 for X).",
      "type": "integer"
    },
    "p_upper": {
      "description": "Maximum p-value threshold (default 5e-8 for genome-wide significance). Use larger values like 0.001 to include suggestive hits.",
      "type": [
        "number",
        "null"
      ]
    },
    "size": {
      "description": "Maximum number of variants to return (default 50, max 1000).",
      "type": [
        "integer",
        "null"
      ]
    },
    "study_accession": {
      "description": "Filter by specific GWAS study accession (e.g., 'GCST002245'). Get study IDs from GWASSumStats_list_studies or GWASSumStats_get_trait_studies.",
      "type": [
        "string",
        "null"
      ]
    }
  },
  "required": [
    "chromosome",
    "bp_lower",
    "bp_upper"
  ],
  "type": "object"
}

Examples (1)

Default GWASSumStats Get Region Associations call

public-safeinput

{
  "bp_lower": 1,
  "bp_upper": 1,
  "chromosome": 1
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_GWASSumStats_get_region_associations
Tool name: GWASSumStats_get_region_associations
Added: 2026-04-30 22:47Z
Tags: tooluniverse

GWASSumStats Get Region Associations

Livelast probed 2026-04-30 23:07Z· 92msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "bp_lower": { "description": "Start position of the region (GRCh38 coordinates).", "type": "integer" }, "bp_upper": { "description": "End position of the region (GRCh38 coordinates).", "type": "integer" }, "chromosome": { "description": "Chromosome number (1-22, or 23 for X).", "type": "integer" }, "p_upper": { "description": "Maximum p-value threshold (default 5e-8 for genome-wide significance). Use larger values like 0.001 to include suggestive hits.", "type": [ "number", "null" ] }, "size": { "description": "Maximum number of variants to return (default 50, max 1000).", "type": [ "integer", "null" ] }, "study_accession": { "description": "Filter by specific GWAS study accession (e.g., 'GCST002245'). Get study IDs from GWASSumStats_list_studies or GWASSumStats_get_trait_studies.", "type": [ "string", "null" ] } }, "required": [ "chromosome", "bp_lower", "bp_upper" ], "type": "object" }