Cortexa research tool·biomedical·gencc

GenCC Get Classifications

Get summary statistics of gene-disease validity classifications from GenCC. Returns counts per classification level (Definitive, Strong, Moderate, Limited, etc.). Optionally filter by gene_symbol (e.g., 'GBA'), disease name substring, or submitter organization. Without filters, returns global stats across all 40,000+ curated submissions.

Livelast probed 2026-05-01 01:00Z· 3577msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 3577ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "disease": {
      "description": "Optional disease name substring to filter classification stats (e.g., 'Gaucher', 'breast cancer')",
      "type": "string"
    },
    "gene_symbol": {
      "description": "Optional HGNC gene symbol to filter classification stats (e.g., 'GBA', 'BRCA2')",
      "type": "string"
    },
    "operation": {
      "const": "get_classifications",
      "description": "Operation type (fixed: get_classifications)",
      "type": "string"
    },
    "submitter": {
      "default": "",
      "description": "Optional filter by submitting organization name (e.g., 'ClinGen', 'Ambry', 'Genomics England')",
      "type": "string"
    }
  },
  "required": [],
  "type": "object"
}

Examples (1)

Default GenCC Get Classifications call

public-safeinput

{
  "disease": "type 2 diabetes",
  "gene_symbol": "BRCA1"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_GenCC_get_classifications
Tool name: GenCC_get_classifications
Added: 2026-05-01 00:58Z
Tags: tooluniverse

GenCC Get Classifications

Livelast probed 2026-05-01 01:00Z· 3577msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "disease": { "description": "Optional disease name substring to filter classification stats (e.g., 'Gaucher', 'breast cancer')", "type": "string" }, "gene_symbol": { "description": "Optional HGNC gene symbol to filter classification stats (e.g., 'GBA', 'BRCA2')", "type": "string" }, "operation": { "const": "get_classifications", "description": "Operation type (fixed: get_classifications)", "type": "string" }, "submitter": { "default": "", "description": "Optional filter by submitting organization name (e.g., 'ClinGen', 'Ambry', 'Genomics England')", "type": "string" } }, "required": [], "type": "object" }