Cortexa research tool·clinical·gencc

GenCC Search Gene

Get gene-disease validity classifications for a gene from GenCC (Gene Curation Coalition). Returns curated evidence levels (Definitive, Strong, Moderate, Limited, Disputed, Refuted) from multiple expert panels including ClinGen, Ambry Genetics, Genomics England PanelApp, and Orphanet. Essential for assessing clinical validity of gene-disease associations in genetic testing.

Livelast probed 2026-04-30 23:07Z· 104msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 104ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "classification": {
      "default": "",
      "description": "Optional filter by classification level (e.g., Definitive, Strong, Moderate, Limited)",
      "type": "string"
    },
    "gene_symbol": {
      "description": "HGNC gene symbol (e.g., BRCA2, TP53, FBN1, CFTR)",
      "type": "string"
    },
    "operation": {
      "const": "search_gene",
      "description": "Operation type (fixed: search_gene)",
      "type": "string"
    }
  },
  "required": [
    "gene_symbol"
  ],
  "type": "object"
}

Examples (1)

Default GenCC Search Gene call

public-safeinput

{
  "gene_symbol": "BRCA1"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_GenCC_search_gene
Tool name: GenCC_search_gene
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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