Genebass Gene Burden Phewas

Exome-wide gene-level burden PheWAS from Genebass (UK Biobank ~394K exomes, SAIGE-GENE+). Given one gene, returns its rare-variant burden association across ~4,500 phenotypes (GRCh38), sorted by p-value. Aggregates rare coding variants into a single gene-level test, complementing single-variant PheWAS. Accepts an Ensembl gene ID (ENSG...) or a gene symbol (auto-resolved via Ensembl). Choose a burden_set: pLoF (predicted loss-of-function, default), missense|LC, or synonymous.