Cortexa research tool·structure·genome_nexus

GenomeNexus Get Canonical Transcript

Get the canonical transcript for a gene from Genome Nexus (MSK). Returns the Ensembl transcript ID, protein ID, protein length, RefSeq mRNA ID, CCDS ID, HUGO symbol, and Pfam protein domain annotations. Useful for determining the standard transcript to use for variant annotation, and for getting a quick overview of protein domain architecture. Input is a HUGO gene symbol (e.g., 'TP53', 'BRAF', 'BRCA1').

Livelast probed 2026-04-30 23:07Z· 101msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 101ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "gene_symbol": {
      "description": "HUGO gene symbol. Examples: 'TP53', 'BRAF', 'BRCA1', 'EGFR', 'KRAS'.",
      "type": "string"
    }
  },
  "required": [
    "gene_symbol"
  ],
  "type": "object"
}

Examples (1)

Default GenomeNexus Get Canonical Transcript call

public-safeinput

{
  "gene_symbol": "BRCA1"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_GenomeNexus_get_canonical_transcript
Tool name: GenomeNexus_get_canonical_transcript
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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