GtoPdb Get Interactions
Get pharmacological interactions between targets and ligands from the Guide to Pharmacology database. Provide gene_symbol (convenience, auto-resolves to targetId), targetId (from GtoPdb_search_targets), or ligandId (from GtoPdb_search_ligands) to filter interactions. Returns binding affinity (Ki, Kd, IC50, EC50), action type (agonist, antagonist, inhibitor, etc.), species, and assay information. NOTE: GtoPdb coverage focuses on GPCRs, ion channels, nuclear receptors, and enzymes; kinase inhibit…
Overview
Get pharmacological interactions between targets and ligands from the Guide to Pharmacology database. Provide gene_symbol (convenience, auto-resolves to targetId), targetId (from GtoPdb_search_targets), or ligandId (from GtoPdb_search_ligands) to filter interactions. Returns binding affinity (Ki, Kd, IC50, EC50), action type (agonist, antagonist, inhibitor, etc.), species, and assay information. NOTE: GtoPdb coverage focuses on GPCRs, ion channels, nuclear receptors, and enzymes; kinase inhibitors (EGFR, BRAF, ALK, VEGFR inhibitors) have limited interaction data — use ChEMBL_get_drug_mechanisms for those instead. No authentication required.
Schema
JSON Schema the agent (or your API call) must match.
Examples (1)
Default GtoPdb Get Interactions call
Anonymous-safe example. Rate-limited; no sign-in required.
Identifiers
- Catalog ID
- tu_GtoPdb_get_interactions
- Tool name
- GtoPdb_get_interactions
- Added
- 2026-04-30 22:47Z
- Tags
- tooluniverse