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Research tool·structure·gtopdb

GtoPdb Get Interactions

Get pharmacological interactions between targets and ligands from the Guide to Pharmacology database. Provide gene_symbol (convenience, auto-resolves to targetId), targetId (from GtoPdb_search_targets), or ligandId (from GtoPdb_search_ligands) to filter interactions. Returns binding affinity (Ki, Kd, IC50, EC50), action type (agonist, antagonist, inhibitor, etc.), species, and assay information. NOTE: GtoPdb coverage focuses on GPCRs, ion channels, nuclear receptors, and enzymes; kinase inhibit…

AvailableCortexa

Overview

Get pharmacological interactions between targets and ligands from the Guide to Pharmacology database. Provide gene_symbol (convenience, auto-resolves to targetId), targetId (from GtoPdb_search_targets), or ligandId (from GtoPdb_search_ligands) to filter interactions. Returns binding affinity (Ki, Kd, IC50, EC50), action type (agonist, antagonist, inhibitor, etc.), species, and assay information. NOTE: GtoPdb coverage focuses on GPCRs, ion channels, nuclear receptors, and enzymes; kinase inhibitors (EGFR, BRAF, ALK, VEGFR inhibitors) have limited interaction data — use ChEMBL_get_drug_mechanisms for those instead. No authentication required.

Schema

JSON Schema the agent (or your API call) must match.

View JSON schemaExpandCollapse
JSON · 41 lines · 1,229 chars

Examples (1)

Default GtoPdb Get Interactions call

Public-safe example · rate-limited

JSON input · 7 lines · 101 chars
Expected response keys: success

Identifiers

Catalog ID
tu_GtoPdb_get_interactions
Tool name
GtoPdb_get_interactions
Added
2026-04-30 22:47Z
Tags
tooluniverse
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