Cortexa research tool·genomics·hpo

HPO Get Term Hierarchy

Get the parent or child terms of an HPO phenotype term in the ontology hierarchy. HPO is organized as a directed acyclic graph (DAG) where more specific phenotypes are children of broader terms. Use direction='children' to find more specific sub-phenotypes, or direction='parents' to find broader categories. Example: children of HP:0001250 (Seizure) include 'Bilateral tonic-clonic seizure', 'Focal-onset seizure', 'Febrile seizure', and others. Parents include 'Abnormal nervous system physiology'.

Livelast probed 2026-04-30 23:07Z· 114msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 114ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "direction": {
      "description": "Direction to traverse: 'children' (more specific terms, default) or 'parents' (broader terms).",
      "type": [
        "string",
        "null"
      ]
    },
    "term_id": {
      "description": "HPO term identifier (e.g., 'HP:0001250'). Must start with 'HP:' followed by 7 digits.",
      "type": "string"
    }
  },
  "required": [
    "term_id"
  ],
  "type": "object"
}

Examples (1)

Default HPO Get Term Hierarchy call

public-safeinput

{
  "term_id": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_HPO_get_term_hierarchy
Tool name: HPO_get_term_hierarchy
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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