Cortexa research tool·genomics·iedb_prediction

IEDB Predict Mhcii Binding

Predict MHC class II peptide binding using NetMHCIIpan via the IEDB Analysis Resource API. Predicts CD4+ T helper cell epitopes. Given a protein sequence and HLA-DR/DP/DQ allele, returns predicted binding peptides ranked by percentile rank. Essential for vaccine design (helper epitopes) and autoimmunity research.

Livelast probed 2026-04-30 23:07Z· 97msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 97ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "allele": {
      "default": "HLA-DRB1*01:01",
      "description": "MHC-II allele. Examples: 'HLA-DRB1*01:01', 'HLA-DRB1*15:01'. Default: HLA-DRB1*01:01",
      "type": "string"
    },
    "method": {
      "default": "netmhciipan_el",
      "description": "Prediction method: 'netmhciipan_el' (recommended), 'netmhciipan_ba', 'nn_align'",
      "type": "string"
    },
    "sequence": {
      "description": "Protein sequence (amino acid letters)",
      "type": "string"
    }
  },
  "required": [
    "sequence"
  ],
  "type": "object"
}

Examples (1)

Default IEDB Predict Mhcii Binding call

public-safeinput

{
  "sequence": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_IEDB_predict_mhcii_binding
Tool name: IEDB_predict_mhcii_binding
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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