InterPro Get Protein Domain Architecture

Overview

Get the complete Pfam domain architecture for a protein with exact residue positions using the InterPro API. Returns all Pfam domains mapped to the protein with start/end coordinates, E-values, and integrated InterPro entries. Much more detailed than simple domain lists - includes precise domain boundaries essential for understanding protein function. Example: P04637 (TP53, 393aa) has 4 Pfam domains: PF00870 (P53 DNA-binding, 100-288), PF07710 (tetramerisation, 319-357), PF08563 (transactivation, 6-30), PF18521 (transactivation domain 2, 35-59).

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed

1d ago

Last success

1d ago

Last latency

118ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "accession": {
      "description": "UniProt protein accession. Examples: 'P04637' (TP53, 4 Pfam domains), 'P00533' (EGFR), 'P38398' (BRCA1), 'P01308' (Insulin).",
      "type": "string"
    }
  },
  "required": [
    "accession"
  ],
  "type": "object"
}

Examples (1)

{
  "accession": "P38398"
}

Identifiers

Catalog ID

tu_InterPro_get_protein_domain_architecture

Tool name

InterPro_get_protein_domain_architecture

Added

2026-04-30 22:47Z

Tags

tooluniverse