Cortexa research tool·structure·klifs

KLIFS Get Structures

Get crystal structures for a specific kinase from KLIFS. Returns all annotated crystal structures with PDB IDs, ligands, DFG-in/out conformation, alpha-C helix orientation, binding site quality scores, and binding pocket fingerprints. Essential for drug discovery - identifies active vs. inactive conformations, Type I/II/III inhibitor binding sites, and DFG-in/out states. Use KLIFS_list_kinases to find kinase IDs.

Livelast probed 2026-04-30 23:07Z· 106msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 106ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "kinase_ID": {
      "description": "KLIFS kinase ID (e.g., 1 for AKT1). Obtain from KLIFS_list_kinases.",
      "type": "integer"
    }
  },
  "required": [
    "kinase_ID"
  ],
  "type": "object"
}

Examples (1)

Default KLIFS Get Structures call

public-safeinput

{
  "kinase_ID": 1
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_KLIFS_get_structures
Tool name: KLIFS_get_structures
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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