LINCS Search Signatures
Search LINCS (Library of Integrated Network-Based Cellular Signatures) for drug perturbation gene expression signatures. Find L1000 and other assay signatures by drug/compound name, optionally filtered by cell line. Returns signature IDs, doses, time points, tissue, disease context, and PubChem IDs. LINCS contains 1.5M+ signatures from 431+ libraries covering thousands of drugs across hundreds of cell lines. Example: searching 'vorinostat' returns HDAC inhibitor signatures across multiple cell…
Overview
Search LINCS (Library of Integrated Network-Based Cellular Signatures) for drug perturbation gene expression signatures. Find L1000 and other assay signatures by drug/compound name, optionally filtered by cell line. Returns signature IDs, doses, time points, tissue, disease context, and PubChem IDs. LINCS contains 1.5M+ signatures from 431+ libraries covering thousands of drugs across hundreds of cell lines. Example: searching 'vorinostat' returns HDAC inhibitor signatures across multiple cell lines and doses.
Schema
JSON Schema the agent (or your API call) must match.
Examples (1)
Default LINCS Search Signatures call
Anonymous-safe example. Rate-limited; no sign-in required.
Identifiers
- Catalog ID
- tu_LINCS_search_signatures
- Tool name
- LINCS_search_signatures
- Added
- 2026-04-30 22:47Z
- Tags
- tooluniverse