MaveDB Get Clinical Controls
Get clinical-control variants (ClinVar pathogenic/benign/VUS) that overlap a MaveDB score set, used to calibrate MAVE functional scores into clinically-interpretable thresholds. Returns ClinVar entries with dbIdentifier, gene symbol, clinical significance (e.g. 'Uncertain significance', 'Pathogenic'), review status, ClinVar version (e.g. '01_2025'), and the MaveDB variant URN(s) sharing the same genomic coordinate. Optionally filter by clinical_significance. This is the reference set for buildi…
Overview
Get clinical-control variants (ClinVar pathogenic/benign/VUS) that overlap a MaveDB score set, used to calibrate MAVE functional scores into clinically-interpretable thresholds. Returns ClinVar entries with dbIdentifier, gene symbol, clinical significance (e.g. 'Uncertain significance', 'Pathogenic'), review status, ClinVar version (e.g. '01_2025'), and the MaveDB variant URN(s) sharing the same genomic coordinate. Optionally filter by clinical_significance. This is the reference set for building functional-score evidence (e.g. ACMG PS3/BS3). Obtain the URN from MaveDB_search_score_sets.
Schema
JSON Schema the agent (or your API call) must match.
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Examples (1)
Default MaveDB Get Clinical Controls call
Public-safe example · rate-limited
Identifiers
- Catalog ID
- tu_MaveDB_get_clinical_controls
- Tool name
- MaveDB_get_clinical_controls
- Added
- 2026-07-29 18:13Z
- Tags
- tooluniverse