NCA Compute Parameters
Perform Non-Compartmental Analysis (NCA) on time-concentration pharmacokinetic data. Computes key PK parameters: Cmax (peak concentration), Tmax (time to peak), AUC0-t (area under curve to last measured point using linear-log trapezoidal method), AUC0-inf (extrapolated), terminal elimination half-life (t½), elimination rate constant (λz), clearance (CL), and volume of distribution (Vd) when dose is provided. Follows FDA/EMA NCA guidelines. Use this when you have raw plasma concentration vs. tim…
Overview
Perform Non-Compartmental Analysis (NCA) on time-concentration pharmacokinetic data. Computes key PK parameters: Cmax (peak concentration), Tmax (time to peak), AUC0-t (area under curve to last measured point using linear-log trapezoidal method), AUC0-inf (extrapolated), terminal elimination half-life (t½), elimination rate constant (λz), clearance (CL), and volume of distribution (Vd) when dose is provided. Follows FDA/EMA NCA guidelines. Use this when you have raw plasma concentration vs. time data from a PK study. Output includes goodness of AUC extrapolation assessment.
Schema
JSON Schema the agent (or your API call) must match.
Examples (1)
Default NCA Compute Parameters call
Anonymous-safe example. Rate-limited; no sign-in required.
Identifiers
- Catalog ID
- tu_NCA_compute_parameters
- Tool name
- NCA_compute_parameters
- Added
- 2026-04-30 22:47Z
- Tags
- tooluniverse