Cortexa research tool·genomics·ncbi_variation

NCBIVariation Spdi Canonical

Get the canonical (normalized) SPDI representation for a variant. Returns the single canonical form of a variant after normalization (right-shifting for indels, using the top-level chromosome sequence). Useful for variant deduplication and consistent storage.

Livelast probed 2026-05-01 01:00Z· 96msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 96ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "spdi": {
      "description": "Variant in SPDI notation to normalize. Examples: 'NC_000001.11:230710047:A:G', 'NM_000546.6:214:C:G' (TP53)",
      "type": "string"
    }
  },
  "required": [
    "spdi"
  ],
  "type": "object"
}

Examples (1)

Default NCBIVariation Spdi Canonical call

public-safeinput

{
  "spdi": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_NCBIVariation_spdi_canonical
Tool name: NCBIVariation_spdi_canonical
Added: 2026-05-01 00:58Z
Tags: tooluniverse

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