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Research tool·genomics·oma

OMA Get Genome Pair Orthologs

Retrieve the complete set of pairwise orthologs between TWO whole genomes (proteome-vs-proteome) in OMA. Unlike OMA_get_orthologs (which returns orthologs of a single query protein), this returns every orthologous protein PAIR between two species genomes -- the data used to build species-pair ortholog tables, dN/dS panels, and comparative-genomics / synteny analyses. Each pair reports entry_1 and entry_2 (omaid, canonical_id, species, HOG/group), the relationship type (1:1, 1:n, n:1, n:m), evol…

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Overview

Retrieve the complete set of pairwise orthologs between TWO whole genomes (proteome-vs-proteome) in OMA. Unlike OMA_get_orthologs (which returns orthologs of a single query protein), this returns every orthologous protein PAIR between two species genomes -- the data used to build species-pair ortholog tables, dN/dS panels, and comparative-genomics / synteny analyses. Each pair reports entry_1 and entry_2 (omaid, canonical_id, species, HOG/group), the relationship type (1:1, 1:n, n:1, n:m), evolutionary distance, and alignment score. Provide species codes (e.g. genome1='HUMAN', genome2='MOUSE') or NCBI taxon IDs. Results are paginated; use per_page and page. Example: genome1='HUMAN', genome2='MOUSE' returns pairs such as HUMAN01436 (NK2R_HUMAN) <-> MOUSE00001 (NK2R_MOUSE), rel_type 1:1.

Schema

JSON Schema the agent (or your API call) must match.

JSON · 31 lines · 813 chars

Examples (1)

Default OMA Get Genome Pair Orthologs call

public-safeinput
JSON · 6 lines · 76 chars
Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID
tu_OMA_get_genome_pair_orthologs
Tool name
OMA_get_genome_pair_orthologs
Added
2026-07-29 18:13Z
Tags
tooluniverse
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