OmniPath Get Complexes

Overview

Get protein complex compositions from OmniPath's comprehensive complex database. Integrates 22,000+ complexes from CORUM, CellPhoneDB, CellChatDB, ComplexPortal, PDB, Guide2Pharma, SIGNOR, KEGG, and other resources. Returns complex names, component proteins with gene symbols, stoichiometry, and database identifiers. Essential for understanding multi-subunit ligand-receptor complexes in cell communication (e.g., heteromeric cytokine receptors). Example: TGFB1 (P01137) participates in 24 complexes including 'TGF-beta receptor II-TGF-beta1 complex' (TGFB1+TGFBR2) and 'ITGAV-ITGB8-MMP14-TGFB1 complex'.

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed

1d ago

Last success

1d ago

Last latency

99ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "databases": {
      "description": "Filter by source database(s), comma-separated. Options: CORUM, CellPhoneDB, CellChatDB, ComplexPortal, Guide2Pharma, PDB, SIGNOR, KEGG-MEDICUS, Cellinker, ICELLNET, hu.MAP, Compleat. Default: all.",
      "type": [
        "string",
        "null"
      ]
    },
    "proteins": {
      "description": "UniProt accession(s), comma-separated. Note: gene symbols are NOT supported for this endpoint; use UniProt IDs. Examples: 'P01137' (TGFB1), 'P00533' (EGFR), 'P01137,P37173' (TGFB1+TGFBR2).",
      "type": "string"
    }
  },
  "required": [
    "proteins"
  ],
  "type": "object"
}

Examples (1)

{
  "proteins": ""
}

Identifiers

Catalog ID

tu_OmniPath_get_complexes

Tool name

OmniPath_get_complexes

Added

2026-05-01 00:58Z

Tags

tooluniverse