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Cortexa research tool·genomics·omnipath

OmniPath Get Enzyme Substrate

Get enzyme-substrate (post-translational modification) interactions from OmniPath. Integrates data from PhosphoSite, phosphoELM, dbPTM, SIGNOR, HPRD, KEA, and other PTM databases. Returns kinase/phosphatase->substrate relationships with specific residue positions, modification types, and supporting evidence. Critical for understanding signaling cascades downstream of receptor activation (e.g., RTK->SRC->downstream phosphorylation targets). Example: SRC kinase (P12931) has 200+ substrates with p…

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Overview

Get enzyme-substrate (post-translational modification) interactions from OmniPath. Integrates data from PhosphoSite, phosphoELM, dbPTM, SIGNOR, HPRD, KEA, and other PTM databases. Returns kinase/phosphatase->substrate relationships with specific residue positions, modification types, and supporting evidence. Critical for understanding signaling cascades downstream of receptor activation (e.g., RTK->SRC->downstream phosphorylation targets). Example: SRC kinase (P12931) has 200+ substrates with phosphorylation sites; LCK (P06239) phosphorylates SOCS3 at Y204 and Y221.

Schema

JSON Schema the agent (or your API call) must match.

JSON · 41 lines · 1,013 chars

Examples (1)

Default OmniPath Get Enzyme Substrate call

public-safeinput
JSON · 1 line · 2 chars
Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID
tu_OmniPath_get_enzyme_substrate
Tool name
OmniPath_get_enzyme_substrate
Added
2026-05-01 00:58Z
Tags
tooluniverse
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