OmniPath Get Intercell Roles
Get intercellular communication roles for proteins from OmniPath. Classifies proteins as ligands, receptors, transmembrane proteins, secreted factors, or extracellular matrix components based on evidence from 40+ databases. Returns functional categories (ligand/receptor/adhesion/transporter), locational annotations (secreted/transmembrane/peripheral), consensus scores, and supporting databases. Critical for identifying which genes act as senders vs receivers in cell-cell communication. Example:…
Overview
Get intercellular communication roles for proteins from OmniPath. Classifies proteins as ligands, receptors, transmembrane proteins, secreted factors, or extracellular matrix components based on evidence from 40+ databases. Returns functional categories (ligand/receptor/adhesion/transporter), locational annotations (secreted/transmembrane/peripheral), consensus scores, and supporting databases. Critical for identifying which genes act as senders vs receivers in cell-cell communication. Example: querying EGFR shows it is classified as 'receptor' by 10 databases with consensus_score 7, plasma_membrane_transmembrane=true; querying TGFB1 shows it is a 'ligand' (secreted=true, transmitter=true).
Schema
JSON Schema the agent (or your API call) must match.
View JSON schemaExpandCollapse
Examples (1)
Default OmniPath Get Intercell Roles call
Public-safe example · rate-limited
Identifiers
- Catalog ID
- tu_OmniPath_get_intercell_roles
- Tool name
- OmniPath_get_intercell_roles
- Added
- 2026-04-30 22:47Z
- Tags
- tooluniverse