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Cortexa research tool·genomics·omnipath

OmniPath Get Intercell Roles

Get intercellular communication roles for proteins from OmniPath. Classifies proteins as ligands, receptors, transmembrane proteins, secreted factors, or extracellular matrix components based on evidence from 40+ databases. Returns functional categories (ligand/receptor/adhesion/transporter), locational annotations (secreted/transmembrane/peripheral), consensus scores, and supporting databases. Critical for identifying which genes act as senders vs receivers in cell-cell communication. Example:…

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Overview

Get intercellular communication roles for proteins from OmniPath. Classifies proteins as ligands, receptors, transmembrane proteins, secreted factors, or extracellular matrix components based on evidence from 40+ databases. Returns functional categories (ligand/receptor/adhesion/transporter), locational annotations (secreted/transmembrane/peripheral), consensus scores, and supporting databases. Critical for identifying which genes act as senders vs receivers in cell-cell communication. Example: querying EGFR shows it is classified as 'receptor' by 10 databases with consensus_score 7, plasma_membrane_transmembrane=true; querying TGFB1 shows it is a 'ligand' (secreted=true, transmitter=true).

Schema

JSON Schema the agent (or your API call) must match.

JSON · 55 lines · 1,416 chars

Examples (1)

Default OmniPath Get Intercell Roles call

public-safeinput
JSON · 1 line · 2 chars
Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID
tu_OmniPath_get_intercell_roles
Tool name
OmniPath_get_intercell_roles
Added
2026-04-30 22:47Z
Tags
tooluniverse
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